الفهرس | Only 14 pages are availabe for public view |
Abstract An unprecedented electrochemical sensor for azithromycin (AM) detection was executed in two different ways. Foremost, by mechanical blending of nano-sized fumed silica (FS) with carbon paste (CP) and secondly by electropolymerization of L-threonine on a carbon paste electrode (CPE). Different electrochemical techniques comprising cyclic voltammetry (CV), chronoamperometry (CA), electrochemical impedance spectroscopy (EIS) and square wave voltammetry (SWV) were utilized in the introduced study in addition to analyses techniques as scanning electron microscope (SEM), energy dispersive X-ray (EDX), transmission electron microscopy (TEM) and X-ray diffraction (XRD). Phosphate buffer solution (PBS) of pH range (5-10) was employed in all AM detections. The limit of detection for FSCPE is 11×10-6 M and for PTCPE is 0.32×10-6 M. Furthermore, outstanding and adequate results were attained for the detec and pharmaceutical drugs.tion of AM in real samples as blood plasma |