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العنوان
Relation between Immunosuppressive CD14+HLA-DRLow/− Monocytes and
IL-10 In Patients With B- Cell Non-Hodgkin Lymphoma
/
المؤلف
El-Faramawy,Mariam Samy Mohammed .
هيئة الاعداد
باحث / مريم سامى محمد الفرماوى
مشرف / لما أكرم الصفدى
مشرف / محمد طريف محمد حمزة سلام
مشرف / شيماء عبد المليك بيصار
مشرف / سلمى عبد الغنى شوكت
تاريخ النشر
2023
عدد الصفحات
159.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة عين شمس - كلية الطب - Clinical Pathology
الفهرس
Only 14 pages are availabe for public view

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from 158

Abstract

Abstract:
Objectives To determine if there is a positive correlation between IL-10 and Immunosuppressive
CD14+HLA-DR Low/− Monocytes levels in B-cell NHL patients.
Materials and methods This study was prospective case control study, conducted between 2019
and 2022, to asses if there is a positive correlation between IL-10 and Immunosuppressive
CD14+HLA-DR Low/− Monocytes levels in B-cell NHL patients who were admitted to hematology
unit of clinical pathology department, Ain Shams University Hospitals, with a new diagnosis of
BNHL and Consent was taken from all patients.
Results No significant relation between CD14+HLADR- monocytes and IL10 serum levels in B NHL patients with p value = 0.117, percentage of CD14+HLADR- monocytes as well as levels of
serum IL10 showed significant difference between cases and controls, p value of 0.001 and <0.001
respectively.
Conclusion Although we couldn’t detect a statistically significant positive correlation between
CD14+HLADR- monocytes and IL-10 in BNHL, but both of them showed a striking elevation in
BNHL patients than controls, leading us to consider these two markers of great value in
hematological malignancies and more researches regarding different subtypes of hematological
malignancies, other non- hematological malignancies and different laboratory parameters could be
very beneficial in cancer research field.
Keywords: BNHL, CD14+HLADR- monocytes,