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المستخلص
This current study suggests that ketofol (ketamine / propofol) concentration at ratios 3:1 and 4:1 may provide effective and safe sedation for patients undergoing ophthalmic procedures under regional anesthesia. An intravenous infusion of a 4:1 ratio is a suitable alternative for delivering ketofol; this provides more stability and consistency of sedation depth and less need for top - up doses that may lead to overshoot of sedation and a delayed recovery. The ratio for the infusion regimen, however, seems best at 4:1 because the overall dose of both drugs required to achieve the same clinical end points is less with a constant infusion, so the ketamine component, which is responsible for the much longer recovery time, can be reduced and a consistent depth of sedation is achieved