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Abstract
Enterococci are Gram positive bacteria that have become an important clinical pathogen and are considered as the second leading cause of healthcare - associated bacteremia with E. faecalis and E. faecium representing the two most common enterococcal species comprising about 5 to 15% of cases of infectious endocarditis, as well as UTIs followed by intra abdominal, pelvic and soft tissue infections. Enterococci have the capacity to acquire resistance to antibiotics including high level resistance to aminoglycosides (HLAR) and glycopeptides including VRE. This evolution of anti microbial resistance in enterococci poses enormous challenges for treatment especially when faced with patients with severe infections. Antibiotics such as linezolid, daptomycin and tigecycline may offer alternative solution for treatment of VRE infections. In the current study we aimed to identify the enterococcal species, determine their antibiotic sensitivity, including HLAR, low susceptibility to vancomycin and detect Ý- lactamase production. In addition we aimed to evaluate therapeutic options for MDR enterococci namely linezolid and tigecycline. Fifty enterococcal species were isolated, E. faecalis 38 / 50, 76% was predominant over E. faecium 12 / 50, 24%