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العنوان
Nano-carrier systems for taste masking of diclofenac potassium /
المؤلف
Nasr Eldin Hussein Nasr Abdelwahab ,
هيئة الاعداد
باحث / Nasr Eldin Hussein Nasr Abdelwahab
مشرف / Aliaa Nabil Elmeshad
مشرف / Nermeen Adel Ahmed
مشرف / Ahmed Roshdy Fares
الموضوع
Pharmaceutics
تاريخ النشر
2022.
عدد الصفحات
155 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
صيدلة
تاريخ الإجازة
16/4/2022
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - PHARMACEUTICS
الفهرس
Only 14 pages are availabe for public view

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from 160

Abstract

Taste is considered a parameter of the most crucial parameters which is significantly affecting patient compliance in case of drugs with poor palatability. Taste masking is a major challenge for the development of orally ingested active pharmaceutical constituent in the field of the pharmaceutical industry. Numerous conventional taste masking techniques have been extensively studied. Affecting the drug solubility or release is a major concern of conventional taste masking techniques. Recently, many nanocarrier systems have been introduced, claiming the advantage of effective taste masking without affecting either the drug solubility or the release.
In order to enhance taste of oral diclofenac potassium (DP) to enhance its compliance, the current study aims to prepare DP liposomes as nanocarrier system for taste masking.
For achieving this goal, the work in this dissertation will be divided into the following chapters:
Chapter (I): Development of Novel Technique for the Preparation of Diclofenac Potassium Liposomes and Their characterization.
Chapter (II): Formulation and Evaluation of Powder for Oral Reconstituted
Suspension of Diclofenac Potassium liposomes