الفهرس 
Introduction & Aim of the workOnly 14 pages are availabe for public view
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Abstract
Nephrologists have traditionally been particularly interested in glomerular disorders (GDs). Both in the poor world and the industrialised world, GDs are well recognised as a leading cause of ESRD. They contribute for almost 10,000 new instances of ESRD each year in the United States, making them the third greatest cause of the disease overall.
Progressive glomerular filtration rate (GFR) decline occurs in just a minority of people with GDs; high-risk patients often have hypertension, significant proteinuria, low estimated GFR (eGFR) upon presentation, or persistent histopathologic alterations (i.e. glomerulosclerosis or tubulointerstitial fibrosis).
In addition to being a main cause of ESRD worldwide, glomerular disorders (GDs) impose a considerable cost on individuals and healthcare systems. In Egypt, neither the GDs themselves nor their results are systematically studied. Because of this, it was of considerable interest to investigate the prevalence and results of GDs, as well as any correlation between chronic renal damage at presentation and GDs outcome.
Patients who presented with biopsy-proven GDs at Minia Nephrology and Urology University Hospital were recruited and prospectively tracked for at least a year, until death or the onset of end- stage renal disease.
Every participant in the research had a complete medical history taken, a physical examination performed, tests run in the lab, and a sample of their kidney taken for histology.
Patients were seen every 2-3 months for clinical evaluation and renal function testing (serum creatinine, estimated glomerular filtration rate, 24-hour urine protein).
Two hundred and eighty-eight patients with biopsy-proven renal disorders were included in the current research, and all of them were followed for the necessary time.
About 38% of all GD cases are attributable to primary GD, whereas 62% were attributable to secondary GD. Secondary GDs were most often brought on by SLE. The most common kind of GN histopathology was diffuse proliferative GN.
By the conclusion of the follow-up period, 67 (33.8%) patients had achieved renal recovery, 51 (25.7%) patients had reached a stationary or progressive course, and 13 (6.5%) patients had progressed to end-stage renal disease.