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العنوان
High resolution MRI for evaluation of malfunctioning ventriculostomy tubes in pediatric/
المؤلف
Abo-Emira,Eman Ahmed Hamed .
هيئة الاعداد
باحث / إيمان أحمد حامد ابوعميره
مشرف / عبير مغاورى عبدالحميد
مشرف / شيماء عبدالستار محمد
مشرف / شروق محمد عوض الله
مشرف / عاصم منير متولى عبداللطيف
تاريخ النشر
2023.
عدد الصفحات
157.p;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة عين شمس - كلية الطب - Diagnostic and Interventional Radiology, and Molecular Imaging
الفهرس
Only 14 pages are availabe for public view

from 157

from 157

Abstract

Background:
Despite the high frequency rate of cerebrospinal fluid shunt malfunction, radiological evaluation of CSF shunts has remained deficient, focusing mainly on demonstrating secondary signs of shunt failure rather than evaluating the shunt tube itself. We aimed to study the utility of different MR pulse sequences in evaluating the cranial and abdominal ends of CSF shunts in order to identify the potential cause of shunt failure and its impact on patient management.
Results:
Twenty-five patients (18 males, 7 females, median age: 2.5 years, IQR: 0.75–15) were enrolled in the study, having 28 ventriculo-peritoneal shunts and single ventriculo-gallbladder shunt. The catheter lumen and fine intraventricular septae were only demonstrated in 3D-DRIVE sequences (p <0.001). Except for three patients (having cranial end-related complications), all patients with cranial and/or abdominal end-related complications received surgery (p <0.001, positive likelihood and negative likelihood ratios= 7.27, 0.3 respectively, sensitivity= 0.7 and specificity= 0.9). MRI findings (luminal occlusion, disconnection, CSF collection or migration) were consistent with operative data. No significant difference between patients who underwent surgery and those with conservative management, or symptomatic and asymptomatic patients in terms of prevalence of ventricular dilatation or white matter signal abnormality. The results of the abdomino-pelvic fat suppressed T2-WI showed excellent agreement with ultrasound findings (Cohen’s Kappa 0.9). Quantitative PC could give insights about CSF dynamics, which depend on the site and cause of shunt malfunction.
Conclusion:
MRI could be a one-stop destination for evaluating patients with suspected non-acute shunt malfunction. It was found to have clinical relevance in terms of accurately locate the exact site and possible cause of shunt related complications.