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Abstract Premature rupture of membrane (PROM), a spontaneous rupture of the amniotic membranes before the onset of active labor, and is prevalent in 8-10% of pregnancies at term (American College of Obstetricians and Gynecologists, 2013). The management of women presenting with PROM is not uniform and women can be offered either an immediate induction of labor or Expectant management until the onset of Labor (Springer et al., 2016). Although immediate induction of labor may have some advantages including shorter time interval from membrane rupture to delivery and a slightly decreased risk for maternal infection (Dare et al., 2006), it was not associated with a decreased risk for CS or adverse neonatal outcome, as compared to expectant management. Therefore, women who desire spontaneous onset of labor can be offered an expectant management. The majority of women progress into spontaneous labor within 24h since PROM onset (Hannah, Ohlsson, Farine et al., 1996 and Keirse MJ et al., 1996). However, some will eventually require induction of labor due to a prolonged latency period as the risk of intrauterine infection increases with the duration of membrane rupture (Seaward, Hannah, Myhr, Farine et al., 1997). |