الفهرس 
Cuprizone-induced Demyelination of the Brain of Male Albino Rat and the Possible protective Role of N-acetylcysteine: Histological and Immune Histochemical Study
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Abstract
Multiple sclerosis is demyelinating autoimmune disease. Fifty adult male albino rats
were grouped: GІ-Control (normal and sham), GII-CPZ (II-A 4Ws); (II-B 8Ws), GIIICPZ and NAC: (III-A- 4Ws); (III-B- 8Ws), GIV (CPZ followed by NAC): (IV-A- 4Ws
CPZ followed by 4Ws NAC) and (IV-B- 8Ws CPZ followed by 8Ws NAC); GV
(Remyelination): (V-A 4Ws CPZ followed by 4Ws no medication) and (V-A 8Ws CPZ
followed by 8Ws no medication) . GII showed CC demyelination, which were reduced
in GIII more than in GIV demonstrating duration dependency.