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العنوان
Preparation and characterization of carboxymethyl chitosan based hydrogels in presence of montmorillonite nanofiller /
الناشر
Heba Mohamed Abdallah Ahmed ,
المؤلف
Heba Mohamed Abdallah Ahmed
هيئة الاعداد
باحث / Heba Mohamed Abdallah Ahmed
مشرف / Magdy Sabaa Wadid Farag Sabaa
مشرف / Nadia Abd El kader Mohamed Rizk
مشرف / Bothaina Mohamed Abd El Moneem Abd El Hady
مشرف / Riham Rashad Mohamed Ali
تاريخ النشر
2017
عدد الصفحات
147 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Organic Chemistry
تاريخ الإجازة
4/10/2017
مكان الإجازة
جامعة القاهرة - كلية العلوم - Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

Crosslinked poly(vinyl alcohol) (PVA) and poly(ethylene glycol) (PEG)/Carboxymethyl chitosan (CMCh) nanocomposites were synthesized using terephthaloyl diisothiocyanate crosslinker, in the presence of montmorillonite (MMT), in different ratios of the two systems. characterization of nanocomposites was performed using different spectral analyses. Swelling behavior was studied in different buffered solutions. It was found that formation of crosslinked CMCh/PVA and CMCh/PEG hydrogels increased the swell ability. Metal ions adsorption has also been investigated. The results indicated that crosslinked CMCh/PVA and CMCh/PEG nanocomposites adsorbed various metal ions much more than non crosslinked CMCh. Antimicrobial activity was examined against Gram-positive bacteria, Gram-negative bacteria, and also against fungi. Results indicated that most of these nanocomposites exhibited good antimicrobial potency. Degradation study was carried out in Simulated Body Fluid (SBF) for different time periods in order to find out the degradation index (Di). Results showed that weight loss of most of the nanocomposites increased as a function of incubation time