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العنوان
New approaches for the synthesis of heterocyclic compounds containing nitrogen and sulfur and assessment of their cytotoxicity /
الناشر
Ahmed Mohamed Mahmoud Abdelkhalek Sarhan ,
المؤلف
Ahmed Mohamed Mahmoud Abdelkhalek Sarhan
هيئة الاعداد
باحث / Ahmed Mohamed Mahmoud Abdelkhalek Sarhan
مشرف / Rafat Milad Mohareb
مشرف / Wafaa M. Hosny
مناقش / Rafat Milad Mohareb
تاريخ النشر
2016
عدد الصفحات
142 P. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
11/9/2016
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 188

Abstract

The thesis contains one original work: New approaches for the synthesis of heterocyclic compounds containing nitrogen and sulfur and assessment of their cytotoxicity. In this work the ethyl 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (1) reacted with phenylisothiocyanate (2) to give the N-phenylthiourea derivative 3.Specialized through the synthesis and cytotoxicity evaluation of new heterocyclic compounds containing nitrogen and/or sulfur with potential biological activities towards some cancer cell lines. Among the synthesized compounds, the thiophene, thiazole, pyrazole, pyridine and pyrimidine derivatives