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العنوان
Outcome of different treatment options for pediatric patients with acute immune thrombocytopenic purpura, Cairo university children hospital, Egypt /
الناشر
Nesreen Mostafa Habib ,
المؤلف
Nesreen Mostafa Habib
هيئة الاعداد
باحث / Nesreen Mostafa Habib
مشرف / Mervat Elsayed Haron
مشرف / Rasha Abdelraouf Abdelaziz
مشرف / Mervat Elsayed Haron
تاريخ النشر
2016
عدد الصفحات
104 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
18/6/2017
مكان الإجازة
جامعة القاهرة - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 128

from 128

Abstract

Background: Immune thrombocytopenia is the most commonly acquired bleeding disorder in children. About 65{u2013}80% of new-onset immune thrombocytopenia children undergo spontaneous recovery within 1 year. Purpose: To compare the efficacy and safety of different treatment options for acute immune thrombocytopenia in pediatrics, in increasing the platelet count, decreasing the severity, frequency or cessation of bleeding. Patients and Methods: Retrospectively, all patients who presented to the pediatric hematology clinic, Cairo university children hospital, with the clinical and laboratory diagnostic features for acute immune thrombocytopenia, during the period from from 1st of January 2014 to 1st of January 2015 were included. All clinical and epidemiological data were abstracted from the medical records. Results: A total of 57 males (55.9%) and 45 females (44.1%) mostly presented with cutaneous bleeding. ITP diagnosis was preceded by upper respiratory tract infection (URTI) which was found in 11 patients (11%). Treatment regimens varied between glucocorticoids (oral or intravenous), IVIG and observation. A total number of 42 patients (41.17%) were counted as lost follow up at the 6th month. Most of them were in complete response. Males showed more response than females at both 3rd month p=0.231 and 6th month p=0.043