الفهرس 
Clinical and biochemical prognostic factors for infants with biliary atresia undergoing kasai portoenterostomy
CONTENTSOnly 14 pages are availabe for public view
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Abstract
Background: Biliary atresia (BA) is a neonatal disease of unknown etiology, where obstruction of the biliary tree causes severe cholestasis, leading to biliary cirrhosis and death in the first years of life, if the condition is left untreated. Aim of work: To assess the outcome and determine the possible clinical and laboratory prognostic factors in cases of BA who performed kasai operation among Egyptian infants. Patients and methods: This study was carried out at the Hepatology Unit, Cairo University Children{u2019}s Hospital, Cairo, Egypt. All cases who were proved to have BA histopathologicaly and performed kasai operation over a period of 3 years were included. Data retrieved from the files included detailed history, general, abdominal examination, growth parameters and laboratory, radiological as well as histopathological investigations at presentation, 3 months and 1-year post kasai follow up. Results: The study included 88 infants, the mean age at time of presentation was 59.6 days. Gallbladder was not visualized or small contracted in 87.6% of the patients by abdominal ultrasound. liver architecture was preserved in 29.5% and severe portal fibrosis was present in 26.1% of the patients which was significaly associated with poorer outcome. Mean age of the patients at time of kasai operation was 81 days