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العنوان
Cord blood albumin and bilirubin as a predictor for neonatal hyperbilirubinemia /
الناشر
Marwa Basher Mostafa ,
المؤلف
Marwa Basher Mostafa
هيئة الاعداد
باحث / Marwa Basher Mostafa
مشرف / Zahraa Mohamed Ezz Eldin
مشرف / Yasmeen Amr Mansi
مشرف / Ahmed Mohamed Ellithy
تاريخ النشر
2016
عدد الصفحات
142 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
10/4/2017
مكان الإجازة
جامعة القاهرة - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 171

from 171

Abstract

Hyperbilirubinemia is the most common cause for readmission during the early neonatal period. Early discharge of healthy term newborns after delivery has become a common practice for socioeconomic reasons. This study was done to evaluate the predictive value of cord blood albumin and bilirubin in identifying infants {u2265}35 weeks for subsequent hyperbilirubinemia. This study is prospective cohort study which carried out on 75 neonates,{u2265}35 weeks. Any mode of delivery, both genders, APGAR score over 7 at the first minute and 10 at fifth minute of life, absence of significant illness or a major congenital malformation. Cord blood sample taken to examine albumin and bilirubin, then another venous sample taken from the neonates after 72 hours delivery to test serum bilirubin. According the levels of cord blood albumin, we found that at cord albumin <2.8 g/dl{u2192}81.8% of cases developed significant hyperbilirubinemia, while with levels >3.3mg/dl was considered safe with no incidence of hyperbilirubinemia. We also found that in the total group, the highest sensitivity (83.3%) was for cut off value of cord bilirubin (1.88mg/dl) with PPV 72.9%,whilst the highest specificity (84.8%) was for cut off value of cord bilirubin albumin (-0.6) with NPV 74.1. In high risk group, the highest sensitivity (88.9%) highest PPV 94.1% and highest specificity (85.7%) with NPV 75%, is for cut off value of cord bilirubin albumin (-0.82). We concluded that cord blood albumin level more than 3.3g/dl is probably safe for early discharge of baby, also we found that the cut off value of cord blood bilirubin albumin in total group (-0.6) have the highest specificity, and in high risk group (-0.82) have the highest sensitivity, specificity and PPV in predicting cases of significant hyperbilirubinemia