الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Endoscopic endonasal skull base surgery is a growing field in which the nasal corridors are used to address skull base lesions. The ladder for skull base reconstructions includes avascular grafts, vascularized pedicled flaps, turbinate flaps, and novel endoscopic regional flaps. Methods: Twenty patients who underwent endoscopic skull base reconstruction for large skull base defects ( more than 1 cm)between May 2013 and January 2016 were divided into two groups treated by Vasculairzed flaps and free grafts and followed for six months for three outcomes that’s; CSF leak , sinonasal symptoms and intracranial infection Results: The use of Vasculairzed local flaps showed more effective separation of the nasal cavity from the cranium as regard CSF rhinorrhea [0% in the flap group and 20% leak in the graft group and meningitis[0% in the flap group and 10 % in the graft group , but have a worse impact on olfaction[ and almost similar effect like free grafts for nasal crustation but less disturbing nasal discharge. Conclusion: endoscopic skull base reconstruction for large skull base defect is more efficiently done by vascularized flaps as a safe and reliable method for separation of the cranium from the nose |