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Abstract Background: Psoriasis is a chronic inflammatory skin condition that is often associated with systemic manifestations. It is considered as a genetic, immunological, systemic disorder with a prevalence of 1{u2013}3% Psoriasis Area and Severity Index is the most commonly used measure to investigate the severity and coverage of psoriasis, and the improvement after therapy.Purpose: The purpose of the study was to culturally translate and validate the Arabic version of PASI scale (and evaluate the test-retest reliability , internal consistency, construct validity ceiling or floor effects of this instruments) in patients with psoraisis to measure psoriasis severity in psorisas patient and to ensure better care delivery. Subject and Methods: One expert panel (each consists of ten experts) and 50 patients with psoriasis participated in this study. Forward translation, development of preliminary initially translated version, backward translation, and development of the pre-final version and testing of pre-final version using experts then testing of the final version on patients were done. Clarity index, expert proportion of clearance, index of content validity, expert proportion of relevance, descriptive statistics, missed item index, time taken to answer the scale, Cronbach{u2019}s coefficient alpha and Spearman{u2019}s rank correlation coefficients were used for statistical analysis |