الفهرس 
Title : Comparative studies to evaluate the equivalency of generic pesticides with special reference to their impurities
CONTENTSOnly 14 pages are availabe for public view
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Abstract
The aim of the study was directed to compare the effect of accelerated storage on the stability of brand and generic fungicides (carbendazim and chlorothalonil). In this respect two technical and three formulations from carbendazim and three formulations from chlorothalonil were selected in this studies. In addition, associated impurities for carbendazim and chlorothalonil were determined. Also, Subchronic effects of both fungicides on male albino rat{u2019}s reproductive system were investigated. Pesticides were stored at temperatures (72±2{u00B0}C for 3 days, 54±2{u00B0}C for 14 days and 35±2{u00B0}C for 3 months). Results indicated that all tested carbendazim were relatively stable under accelerated storage except for the formulation (Kemazid 50% WP) was markedly deteriorated when storage at 72±2{u00B0}C for 3 days and 35±2{u00B0}C for 3 months. Regarding the carbendazim impurities (2-amino-3-hydroxy-phenazine and 2,3diaminophenazine) were not detected in all samples. Chlorothalonil active ingredient it is stability not affected after storage stability test where the percentage loss of chlorothalonil was about 0.11% to 1.64% in all tested formulations. The percentage of hexachlorobenzene in chlorothalonil formulations, Open 72% SC formulation before and after accelerated storage was above the FAO limit. Concerning the subchronic effect of Carbendazim and chlorothalonil which, were orally administered to male rats daily for 65 successive days