Search In this Thesis
   Search In this Thesis  
العنوان
Evaluation of interleukin-10 and transforming growth factor-Ý in human hepatocellular carcinoma cell line subjected to ”sorafenib-taurine” therapeutic model /
الناشر
Ahmed Motawa Eisa Elhouseini ,
المؤلف
Ahmed Motawa Eisa Elhouseini
هيئة الاعداد
باحث / Ahmed Motawa Eisa Elhouseini
مشرف / Ahmed Mohamed Fathi Afifi
مشرف / Reda Hasan Tabashy
مشرف / Mohamed Ahmed Khalil
مناقش / Hamed M.O.Fayed
تاريخ النشر
2018
عدد الصفحات
101 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
27/2/2018
مكان الإجازة
جامعة القاهرة - كلية العلوم - Zoology
الفهرس
Only 14 pages are availabe for public view

from 176

from 176

Abstract

Sorafenib (Sor) is a multi-kinase inhibitor, it is recommended for the treatment of advanced hepatocellular carcinoma (HCC). However, Sor has severe and marked side effects. Taurine (Tau) has been shown to enhance the therapeutic effects of cancer chemotherapy and also to enhance the function of leukocytes. Aim of the study: The present study aimed to investigate the immunological aspects of Sor, Taurine as well as after combination on human hepatocytes. Materials and Methods: HepG2 cell line was cultured to determine IC50 using SRB assay. The levels of TGF-Ý and IL-10 released in culture media of the cells were determined by ELISA