الفهرس 
REVIEW OF LITERATUREOnly 14 pages are availabe for public view
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Abstract
The objective of this study was summarized in the following points:
- Studying the antibiotic susceptibility pattern of foodborne pathogens isolated from food products available in Cairo or Egypt
- Evaluation of the probiotic characteristics of five Lactobacillus
strains
-Screening the antimicrobial activity of selected lactic acid bacterial against foodborne pathogenic bacteria found in food
- Assessment the inhibition of pathogens-adhesion to the Caco-2 cell line by probiotics
from 20 kinds of food products, 54 foodborne pathogenic bacteria belong to seven genera as follows; (Escherichia coli, Staphylococcus aureus, Bacillus cereus, Proteus. Pseudmonas, Shigella, and Klebsiella)
All selected isolates were resistant to Amoxicillin and Ampicillin and were susceptible to Imipenem.
The study succeeds to isolate and identify five probiotics; Lactobacillus pentosus strain K50, Lactiplantibacillus plantarum strain Gm6, Lactobacillus plantarum subsp. plantarum strain Ni1243, Lactiplantibacillus argentoratensis strain LSM1-4, and
Lactobacillus plantarum strain KK518. They showed a good tolerance to acidic medium and bile salts (PH= 2 & 0.3%) after 2 hr and 4hr of incubation; the latter is more observe than the former. With a survival rate of 78%, Lactobacillus plantarum subsp. plantarum strain Ni1243 had the strongest resistant to low pH and bile salts.
All selected probiotics were resistant to Vancomycin, Amoxicillin-clavulanic acid, and Ciprofloxacin, and sensitive to Imipenem, and intermediate sensitivity to Gentamycin.
Lactobacillus pentosus strain K50, Lactobacillus plantarum strain KK518, and Lactiplantibacillus plantarum strain Gm6 showed the ability to tolerate to phenol with concentration 0.4% than phenol with 0.6% while Lactiplantibacillus plantarum strain Gm6 and Lactobacillus plantarum subsp. plantarum strain Ni1243 showed the ability to tolerate phenol with 0.6%.
The agar spot test was used to investigate the antagonism of LAB to isolated foodborne pathogens, and the results revealed that LAB may suppress the development of foodborne bacterial pathogens to varied degrees.
Results of adhesion of five Lactobacillus strains showed that Lactiplantibacillus plantarum strain Gm6 was the most adherent to the Caco-2 cell line, whereas Lactiplantibacillus
argentoratensis strain LSM1-4 was the least adherent. Lactobacillus had a positive effect on a variety of pathogenic bacteria isolated from a variety of retail goods gathered from local markets, including Staphylococcus aureus, Klebsiella, and Escherichia coli, and might be used as a natural antibiotic alternative.
All of the probiotics and foodborne pathogen strains under investigation could adhere to the Caco-2 cell line, and co- culturing the adhesion of selected lactobacillus was at the expense of the pathogen
Results showed that Lactobacillus plantarum subsp. plantarum strain Ni1243 had the ability to reduce the most adhesion efficiency of pathogenic bacterial isolates.