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العنوان
Evaluation of central versus distal pancreatectomy in management of pancreatic body tumors :
المؤلف
El-Yamany, Mohamed Abd El-Latif Abas.
هيئة الاعداد
باحث / محمد عبداللطيف عباس اليماني
مشرف / أمجد أحمد فؤاد
مشرف / طارق صلاح الحسيني
مشرف / علي سالم علي
مشرف / محمد السيد الدسوقي
الموضوع
Pancreatic Neoplasms. Pancreatectomy. Pancreaticoduodenectomy. Medicine. General surgery. Pancreatic body tumors.
تاريخ النشر
2022.
عدد الصفحات
online resource (105 pages) :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
جراحة
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة المنصورة - كلية الطب - الجراحه
الفهرس
Only 14 pages are availabe for public view

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Abstract

The standard surgical treatment for low-grade malignant or benign masses located in the pancreatic body or neck is often associated with diminishing of endocrine and exocrine functions. Central pancreatectomy has been evolved to preserve the normal pancreatic tissue to decrease the risk of the previous insufficiencies. Aim of the Work : This study was conducted to evaluate the early and late post-operative results of central pancreatectomy in comparison of distal pancreatectomy in management of pancreatic body tumors. Material and Methods : We included a total of 70 subjects diagnosed with pancreatic body or neck masses, who were subdivided into two groups ; group A involved 35 patients undergoing mid or central pancreatectomy, while group B involved 35 patients undergoing the distal pancreatic resection. Results : Most preoperative parameters were statistically comparable between the two groups. Operative time showed mean estimates of 232.8 and 202.2 min. in A and B Groups, in that order, with a significant prolongation in association with the central pancreatectomy procedure. Intraoperative blood loss and need for blood transfusion did not express significant differences between the two groups. ICU admission and the duration of hospitalization showed a significant increase with group A. However, the incidence of complications was statistically comparable between the two procedures, as it was encountered in 45.7% and 42.9% of patients in Groups A and B respectively. Hospital readmission was required in 22.9% and 5.7% of patients in Groups A and B respectively. The incidence of both endocrine and exocrine deficiencies showed a significant increase in group A compared to the other group. Conclusions : Central pancreatectomy can be selected carefully as an appropriate surgical option for benign and borderline malignant lesions limited to the pancreatic body/neck area. It is associated with a significant beneficial impact on post-operative pancreatic endocrine and exocrine functions without increased complication rates.