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العنوان
Evaluation of the effect of nanocarrier system of selective COX-2 inhibitor in combination with tricalcium phosphate in the treatment of intrabony defects :
المؤلف
Ahmed, Radwa Ismail.
هيئة الاعداد
باحث / رضوى اسماعيل أحمد عبدالحكيم
مشرف / محمد عبدالمنعم ابراهيم
مشرف / أحمد عبدالله خليل
الموضوع
Oral Surgical Procedures.
تاريخ النشر
2022.
عدد الصفحات
133 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأسنان
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة المنيا - كلية طب الأسنان - طب الفم والتشخٌيص
الفهرس
Only 14 pages are availabe for public view

from 134

from 134

Abstract

Ongoing periodontitis is described via using lack of clinical connection because of annihilation of the periodontal tendon and lack of adjacent supporting bone, and affects almost ninety% of the population .
The remaking or reclamations of those deformities brought about by way of provocative periodontal sickness is a intending with venture in periodontal remedy. This objective can be finished thru utilizing regenerative surgical operation like root biomodification, usage of bone substitution unites, Guided tissue recovery (GTR) and improvement elements.
β-TCP has been supplied inside the periodontal field as a biocompatible alloplastic bone joining material that is resorbable with osteoconductive homes , consequently, it’s miles idea of as a fantastic preference in evaluation to autografts or allografts for unique uniting tactics.It’s been displayed to undergo whole resorption and is supplanted by way of the use of bone inner a time of zero.Five-1.5 years while implemented to precise hard imperfections, for example, intraosseous deserts round everyday tooth, edentulous broken alveolar edges, and maxillary sinuses.
Discoveries from human clinical examinations have uncovered that treatment of infra-tough deformities with TCP materials could likely result in critical attempting out pocket profundity (PPD) and profundity of rigid decreases with big clinical connection degree (CAL) profits.
Celecoxib is a non-steroidal mitigating drug that particularly restrains COX-2 and that has ache relieving, calming and antipyretic affects. It’s been accounted for that this medicinal drug restrict osteoclast improvement and straightforwardly have an impact on bone resorption.
The contemporary overview have become led to assess the effect of nanocarrier arrangement of precise COX-2 inhibitor in mixture with tricalcium phosphate within the remedy of intrabony surrenders in slight of medical obstacles and alveolar bone adjustments making use of CBCT.
Thirty patients of the 2 genders and a long time going from 25-fifty five years have been selected in this assessment. Sufferers were analyzed as having diploma III periodontitis with somewhere round contralateral rakish intrabony absconds have been arbitrarily alloted with β-TCP handiest for bunch I even as the alternative amassing changed into handled with the resource of β-TCP .+ Celecoxib gel. Medical barriers such as gingival record, plaque record, inspecting pocket profundity and clinical connection degree had been recorded at the underlying duration of remedy and throughout the evaluation period in three and a 1/2 12 months positioned up a clinical approach. Radiographic imperfection profundity , deformity thing and photograph electricity of ROI estimations had been finished at state-of-the-art and a 1/2 of 12 months maintaining a scientific method making use of CBCT.
Our review showed that there was improvement in medical obstacles by way of the usage of time from benchmark to a half of year. With recognize to radiographic barriers, the DD . DA and picture pressure are labored on in the two gatherings. But, greater development effects acquired from bunch II (β-TCP+ Celecoxib ) from gauge to a half of yr and the assessment among the 2 gatherings are measurably big.