الفهرس 
Title : Value of hepatitis C core antigen in detection of chronic hepatitis C virus eradication state post treatment
ContentsOnly 14 pages are availabe for public view
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Abstract
Background & Aim: HCV core antigen is a marker for HCV infection. The current study aimed at evaluate the clinical utility of hepatitis C core antigen in detection of chronic hepatitis C virus at pre-treatment and post DAAs (SVR12) using Core Antigen ELISA. Methods: 185 patients with chronic HCV (92 in pre-treatment and 93 in post treatment) attending to Kasr Al Ainy Viral Hepatitis Center (KAVHC) Faculty of Medicine,Cairo University in the period from January 2019 till April 2019 were enrolled and subjected to demographic, clinical, laboratory assessment and abdominal ultrasound . In addition, HCV Core Ag was measured by ELISA method at pre-treatment and post DAAs treatment. Results: In the current study, a total sample of 185 HCV-Ab positive, 92 at pretreatment phase, only 73 patients were HCV-RNA positive, 32 of them were HCVcAg positive while 19 patients were HCV-RNA negative, 8 of them were HCVcAg positive and 11 were negative, sensitivity of HCV Core Ag was 43.8% in pre-treatment phase while specificity was 57.9 %.In contrast to the post treatment patients, 93 were all negative HCV-RNA and only 20 of them were positive HCVcAg and 73 were negative HCVcAg