الفهرس 
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Abstract
The aim of the study was evaluation of serum levels of anti-Mullerian hormone in Azoospermic patients and its ability to predict sperm retrieval in non-obstructive azoospermia.
This was conducted as a comparative study in Andrology outpatient clinic at Beni-Suef University hospital and Andrology outpatient clinic at El Kasr Al Aini Hospital. Patients were to be enrolled into the study starting from June 2021 until May 2022. This study included 90 married males with azoospermia 45 patients with functional azoospermia and 45 patients with obstructive azoospermia after institutional approval and informed consent.
Overall, 90 men were allocated into: -
obstructive azoospermia (n=45).
functional azoospermia (n=45).
Inclusion criteria
1. Age of patients (males between 25 to 45 years old).
2. Patients married for at least one year ago with no conception.
3. Patients with clinical and laboratory data indicating non-obstructive azoospermia or obstructive azoospermia.
Exclusion criteria
1. Patients with chronic illness (eg. chronic kidney, liver or heart diseases).
All patient were subjected to :
1-History taking.
2- General and clinical examination.
3-Semen analysis according to WHO guidelines (2010).
4- Determination of serum Anti-Mullerian Hormone:
3 ml of venous blood samples will be collected after patient approval, and then serum is separated to measure level of Anti-Mullerian Hormone by ELISA technology.
The results of our present study can be summarized as follows:
The current study showed that, regarding the Pathology result, 55.6% were Germ cell aplasia (Sertoli cell only), 20% were Hypospermotogenesis, 20% were Primary spermatocyte arrest, 2.2% were Marked Hypospermotogenesis, and 2.2% were Normal Spermatogenesis. For the Sperm retrieval, 75.6% were Negative and 24.4 % were Positive.
The current study showed that, there was highly statistically significant difference found among Obstructive azoospermia than Functional azoospermia regarding AMH Level.
Our results showed that, there was no statically significant correlation between AMH Level and BMI.
The present study revealed that, there was no statistically significant difference found between AMH Level and Sperm retrieval.
Receiver operating characteristic curve (ROC) shows that the best cut off point of AMH Level to detect Functional azoospermia group was found <=3.2 with sensitivity of 51.1%, specificity of 95.6%, PPV of 92.0%, NPV of 66.2% and total accuracy of 70.0%.