الفهرس 
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Abstract
Liver fibrosis represents a major medical problem worldwide that is associated with significant morbidity and mortality. It appears to play a direct role in the pathogenesis of hepatocellular dysfunction and portal hypertension. Thus assessing the extent and progression of fibrosis is important.
Liver biopsy is the gold standard for fibrosis staging, although it is limited by its invasive nature, poor acceptance, availability, cost, intra- and interobserver variability, and sampling errors.
Our study included 34 chronic HCV patients as diagnosed by seropositivity for HCV antibodies and HCV RNA by PCR. Patients were referred from NHTMRI for assessment prior to viral therapy and they underwent liver stiffness measurement using fibroscan and ultrasound guided liver biopsy.
In our study the correlation of liver biopsy results with fibroscan scores showed high significant agreement; the best agreement was in fibrosis stage 4 and the worst agreement was in fibrosis stage 2.