الفهرس 
Effect of vinica alkaloids iontophoresis on post mastectomy shoulder pain
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Abstract
Aim: The aim of this study was to evaluate effect of vinica alkaloids iontophoresis on post mastectomy shoulder pain. Subjects and Methods: A randomized controlled study was carried out, thirty females with age range from 35 to 50 years and suffering from shoulder pain post mastectomy were chosen and randomly divided into two equal groups, each one included 15 patients. Patients in group A (Study group) received 45-60 minutes of vinblastine iontophoresis (20ml vinblastine) 3times/ week in addition to conventional medical care, for eight weeks while and group B (Control group) received placebo 45-60 minutes of only (20 ml saline) iontophoresis (3times/week), in addition to conventional medical care, for eight weeks. Methods of assessment included Visual analogue scale (VAS) and Goniometer for shoulder pain and range of motion (ROM) respectively. Patients in both groups were assessed before treatment and after 8 weeks of treatment.Results: Significant improvements in VAS and shoulder ROM were reported in the study group compared to the control group (p > 0.001). In the study group, the percent of improvement of shoulder flexion, abduction, internal and external rotation was 22.9%, 24.62%, 35.85%, and 39.97% respectively, while in the control group was 0.5%, 0.67%, 2.8%, and 3.35% respectively. VAS scores achieved higher percentage of improvement (54.05%) compared to control group (10.15%). Conclusion: Vinica alkaloids iontophoresis achieved significant improvements in shoulder pain and ROM following mastectomy