الفهرس 
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Abstract
With the increasing prevalence of obesity, diabetes mellitus and the metabolic syndrome in the general population, non-alcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease. Establishing a link between liver and kidney injury would enhance the earlier identification of kidney disease and allow for the selection of treatments targeting both liver and kidney disease with potentially relevant preventive and therapeutic implications. The current study aimed to evaluate microalbuminuria as an early detector of renal affection in patient with non alcoholic fatty liver disease (NAFLD) The current study included 114 patients, presented to Assuit university hospital –Internal medicine department with fatty liver disease diagnosed by abdominal ultrasonogarphy and lab investigations. The mean age of the current study patients was 47.2 ± 11.6 years. There were 55.3% males. The mean weight, height and BMI of the patients were 80.7 ± 7.3 kg, 1.7 ± 0.1 meter and 26.6 ± 3.8 kg/m2, respectively Liver echogenicity of the patients was bright in 85.1% of the cases and it was normal in 14.9% of cases. Also, the median liver span was 16 and a mean of 16.3 ± 0.8 cm. It was found that the kidney size and echogenicity were normal in all patients according to the US findings In the present study the mean haemoglobin level, WBCs count and platelet count were 12.6 ± 1.7,6.9 ± 1.8 *109 and 290.5 ± 67.8 *103. The mean blood urea level was 3.90 ± 1.1 mg/dl. The mean serum creatinine was 73.6 ± 19.3 mg/dl. As well, e-GFR ranged from 54.2 to 142 with a mean of 97.7 ± 21.7.Albuminuria ranged from 5 to 52 mg/g. 17.5% of this study population showed microalbuminuria (albuminuria > 30 mg/g). Cholesterol level, TGD, HDL level and LDL were 179.1 ± 23.4 mg/dl, 150.4 ± 47.1, 48.4 ± 11.9 mg/dl and 100.8 ± 25.3 mg/dl, respectively.The mean AST, ALT level, Total bilirubin, direct bilirubin level and albumin level were 22.6 ± 13.1 U/L, 26.3 ± 23.3 U/L, 1.01 ± 1.0 mg/dl, 0.5 ± 0.3 mg/dl and 40.7 ± 4.5 g/L Total protein level ranged from 60 to 68 g/dl with a mean of 44.2 ± 34.4 g/dl. Besides, ALP level ranged from 40 to 804 IU/L with a mean of 88.7 ± 70.1 and a median of 81 IU/L. In this study INR ranged from 0.6 to 1.4 with a mean of 1.04 ± 0.8. Additionally, PC ranged from 89 to 121% with a mean of 98.2 ± 12.9%.Likewise, PT ranged from 10 to 15 seconds with a mean of 12.3 ± 1.2 seconds. Patients with NAFLD who developed AKI in the current study were insignificantly older than patients who did not.