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العنوان
Management Strategies for Electrical Status Epilepticus during Sleep in Assiut University Children Hospital /
المؤلف
Randa Abdelbadie Abdelaleem Osman Kandiel
هيئة الاعداد
باحث / راندا عبدالبديع عبدالعليم عثمان قنديل
مشرف / السيد خليل عبدالكريم
مناقش / عماد الدالي
مناقش / هدى طموم
الموضوع
for Electrical Status Epilepticus.
تاريخ النشر
2022.
عدد الصفحات
125 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
الناشر
تاريخ الإجازة
13/6/2022
مكان الإجازة
جامعة أسيوط - كلية الطب - طب الأطفال
الفهرس
Only 14 pages are availabe for public view

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from 125

Abstract

In the present study, we aimed to assess the neurocognitive function of ESES patients and whether there was any relation between SWI and IQ and to evaluate the effect of oral steroids and IVIG on normalization of sleep EEG and improvement of seizure control and neurocognitive functioning Fifty patients (33 males and 17 females) were diagnosed as electrical status epilepticus of sleep at the pediatric neurology outpatient clinic of Assiut University Children Hospital and their ages ranging from 2 to 15 years from January 2018 until December 2020. The mean age at time of diagnosis of ESES was 6.19±2.80 SD. It was found to be more common in male patients (66%) than female patients(34%)Regarding the developmental history prior to ESES diagnosis, 25 (50%) patients were normal, and 25 (50%) were delayed. 48 patients presenting with ESES had seizures, while two cases presented with regression of previously attained skills, without any seizures. The mean age (years) at the time of first convulsions was 3.36±2.93 SD. 73% of the patients had generalized seizures, while 23% had focal seizures, and 4% had mixed seizure types. Regarding occurrence of convulsions in relation to sleep, 27% occurred during sleep, 50% during awake, and 23% occurred both in sleep and awake Of the 50 patients, 58% (29 patients) had normal neuroimaging, while 42% (21 patients) had an abnormal neuroimaging finding. Brain atrophy, operated hydrocephalus, and tuberous sclerosis (42%, 9%, 9% respectively) were the most common abnormal findings As regards the type of neurocognitive regression (34 patients), the most common observed was speech regression (9 patients or 26.4%), hyperactivity (8 patients or 23.5%) and global (motor and speech) regression (8 patients or 23.5%).