الفهرس 
Chapter 1: Physiology of lung fluidOnly 14 pages are availabe for public view
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Abstract
ABSTRACT
Background: Transient tachypnea of the newborn (TTN) is a neonatal lung disease which has a picture of lung edema due to delayed resorption of lung fluids.
TTN is an important cause of respiratory distress in the neonates, Most of the cases are benign, self-limited, but there are rare incidence of developing severe respiratory distress which denotes that the neonate had malignant transient tachypnea of newborn.
Objective: This a prospective case control study aimed to measure serum lactate and lactate dehydrogenase level as markers for early diagnosis and assessment of severity of transient tachypnea of newborn.
Subjects and methods: The study was performed on 50 neonates with evidence of TTN admitted in the Neonatal Intensive Care Unit (NICU) of Fayoum governorate Hospitals as a case group and 50 healthy neonates as a control group. Detailed history and meticulous general & systemic examinations were done. Complete blood count, serum lactate and lactate dehydrogenase level were analyzed by ELIZA and chest X-ray was done.
Results: lactate and LDH were statistically significant as predictors for TTN among the study groups as regarding with sensitivity of serum lactate was 64% and specificity was 76% with p value was <0.0001 and cut-off point was 1.42. Sensitivity of serum LDH was 60% and specificity was 50% with p value was
0.102 and cut-off point was 669 in diagnosis of TTN.
Conclusion: There was a significant difference in the percentage of serum lactate and LDH between the case and control groups so they can be considered a useful predictors for diagnosis of TTN.
Key words: TTN, serum lactate and LDH.