الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 68 |  |  |
| | | from | 68 | | |
Abstract
Pre-eclampsia is a disease associated with hypertension and protein in urine after twenty weeks of gestation which affects about 5–14 % of all pregnant women and considered a common cause of maternal and fetal morbidity and mortality. Depending on clinical presentation, preeclampsia is described as a late pregnancy disease; however the molecular pathology causing its onset seems to occur early in pregnancy. Maternal manifestations of preeclampsia are considered a result of placental affection associated with poor placentation, inflammatory process and ischemic changes leads to hypoxia and trophoblastic damage.
This study was designed for evaluation the serum level of CD4+ cells CD8+ cells in addition to CD4+ cells/CD8+ cells ratio in patients with severe preeclampsia compared with pregnant women with normal blood pressure at third trimester and to correlate of CD4+ cells level, CD8+ cells in addition to CD4+ cells/CD8+ cells ratio with severity of pre-eclampsia.
The patients were collected from El-Shatby Maternity University Hospital. They were divided into two categories in the third trimester, category A: twenty five severe preeclamptic patient and category B: twenty five normal pregnant women.
All patients (n=50) underwent complete history taking, clinical examination, ultrasound examination for fetal biometry, mean gestational age, estimated fetal weight, estimation of amount of liquor and umbilical artery doppler ultrasonography.
Laboratory investigations were done involving complete blood count, liver function tests, kidney function