الفهرس 
): Basic Physiology of ThiamineOnly 14 pages are availabe for public view
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Abstract
Background : Laparoscopic Mini-Gastric Bypass is considered as a restrictive & mal-absorptive technique with excision of most of the stomach plus bypassing about 2 meters of small intestine including ( duodenum and jejunum) . The main complication is the Vitamins and micronutrients deficiency as Thiamine (vit. B1) . These deficiencies caused by many causes as mal-absorption with Mini Gastric Bypass due to bypassing the site of thiamine absorption .
Aim of work : The study aims to determine the impact of Mini-Gastric Bypass on thiamine (vit. B1) absorption and deficiency.
Patients and Methods : A Prospective study was included 15 patients presented for Mini-Gastric Bypass Surgery At Ain Shams hospitals and Kafr El Sheikh General Hospital from October 2020 to October 2021 . Clinical history was obtained that included demographic data , history of pre-operative vitamin deficiency and comorbid diseases .
Diagnosis of Thiamine deficiency was by measuring thiamine at 3 and 6 months postoperative . All patients had performed Mini-Gastric Bypass operation with intraoperative parameters : Bilio-Pancreatic limb of 2 meters is bypassed. Patients postoperatively were ensured for daily supplement of oral thiamine.
Results : The mean age of the studied group was 35 years. (55%) of them were females and (45%) males. The mean BMI was 40 kg/M2 .
No one of the study cases had thiamine deficiency preoperative , all showed normal total thiamine level ( 3.2 – 9.5 ug/dl ) .
The results postoperative show 100 % of cases show deficiency in total thiamine level 3 & 6 months postoperative.
The Mean Excess Weight Loss percentage ( EWL % ) shows increase in loss about 36 % , 56% , 3 and 6 months postoperatively respectively .
Conclusion : Mini-Gastric Bypass is an effective operation in losing weight in the first postoperative months , despite of that is corresponding early significant deficiency of thiamine ( Vit. B1) , one of the most important vitamins for energy and neurological integrity .
Deficiency of thiamine may show neurological deficits symptoms