الفهرس | Only 14 pages are availabe for public view |
Abstract Heterocyclic compounds containing nitrogen atom are one of the most important resources for new drugs. They are used to develop a new azodyes based on acridine chromophore for applications in printing and in-vitro antibacterial screening. Furthermore, the electrochemical measurements were studied and achieved to identify the electrochemical behavior of the azo-disperse dyes. The electrochemical degradation was also studied. This thesis contains three parts. Part One The introduction part represents a general background on acridine compounds, biological applications and its analogues. It is also illustrate a brief background concerning dyes, their classifications, electrochemical detection, harmful effects on environment and an electrochemical method for their removal. Part Two It describes the experimental section which contains the methodology, materials and solvents for the preparation of acridine disperse-dyes for organic and electrochemical studies. Furthermore, acridine azocompounds characterization were studied by FT-IR, NMR, and mass spectral analysis. The application of these dyes on polyester fabrics was also studied. The invitro anti-bacterial screening of the printed dyes towards Gram (+) and Gram (-) pathogens was also recorded. In addition to, the preparation of poly1,2-DAAQ/GC electrode and the electrochemical behavior and degradation of azodye 10c, CPE analysis and UV-Vis analysis were illustrated. Part Three Illustrates results and discussion part of the synthetic methods of acridine dyes and the spectroscopic analysis for the azo compounds. Development methods for the synthesis of the disperse dyes and suggested mechanisms for the formation of the final products were also mentioned and discussed. In addition to, the electrochemical behaviour of 10c using GC electrode and poly 1,2-DAAQ/GC electrode was performed. The effect of scan rate, concentration and analytical measurements were detected. The removal of dye 10c was conducted using controlled potential electrolysis (CPE) technique at the both mentioned electrodes. These experiments were followed by using UV/Vis technique before and after removal treatment. |