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العنوان
THE ASSOCIATION OF GUT MICROBIOTA 16s RNA TARGET REGION WITH OBESITY /
المؤلف
Soliman, Manal Gaber.
هيئة الاعداد
باحث / منال جابر أحمد سليمان
مشرف / سناء سيد جزارين
مشرف / إيمان عبد الفتاح بدر
مشرف / وليد عبد المحسن شهاب الدين
الموضوع
Internal Medicine. Obesity.
تاريخ النشر
2021.
عدد الصفحات
116 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
الناشر
تاريخ الإجازة
21/8/2021
مكان الإجازة
جامعة المنوفية - كلية الطب - الباطنة العامة
الفهرس
Only 14 pages are availabe for public view

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from 162

Abstract

Gene of 16s rRNA is an important component factor of the
transcription process of all DNA-dependable life organisms. It
represents a target gene for DNA sequencing in samples that contain
more than thousands of different species. This gene helps in
discrimination among specific different microorganisms as archaea,
bacteria, and microbial eukarya. However the identification of viruses
needs sequencing of metagenom (it is a direct DNA extracted
sequencing from a community of microorganisms) as their deficiency
of the phylogenetic marker of 16S rRNA gene.
This work aimed to study the possible association of gut
microbiota 16S rRNA target region with obesity. The abundant gut
microbiota in lean, obese, and obese with DM subjects.
Obesity is defined as a medical state that happen when a person
has an excessive body weight or fat that may affect his health status. An
obese person has a high body mass index, which is a tool used to
recognize if a person has an ideal weight for his age, sex, and height.
Normal BMI is from (18.5-24.9). Persons with BMI (25-29.9) are
considered overweight. BMI is more than or equal 30 is classified as
obese. There are other measures to detect the obesity like the, BF%, and
fat distribution all over the body involved to determine healthy obesity
and non-healthy one.
Numerous studies have demonstrated a link between microbiota
and obesity. Obese subjects show reduced richness and diversity of
GM, with an alteration in the specific pattern of the main phyla found
in humans and rodents.
Gut microbiome has an important role on the following four
broad areas which are corner stones of human health:
Nutrition, Immunity, Behavior, and Diseases.