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Abstract Meniscal injuries are the most common intra-articular knee injury, With the mean annual prevalence has been reported to be 66 per 100,000, men are more prone to meniscal lesions than women, with a male to female prevalence ratio between 2.5:1 and 4:1. The avascular nature of the meniscus poses a significant challenge for meniscus tear healing, as only the peripheral 10–30% of the meniscus is vascularized, may heal on its own,where as tears in the white zone do not have a rich blood supply and more often need further management. Management of meniscal tears includes operative measures, such as meniscectomy and meniscal repair/reconstruction, and more conservative measures, analgesics, activity modification, physical therapy, and intra-articular injections of Corticosteroids, hyaluronic acid, and platelet-rich plasma. In recent years, there has been growing interest in the role of orthobiologics in the treatment of meniscal pathology. There are several modalities for biologic augmentation of meniscal repair, including use of a fibrin clot, cytokines, growth factors and PRP. The use of imaging guidance, in particular ultrasound, improves the accuracy of intra-articular injection in large joints, including the knee. Furthermore, accurate ultrasound-guided intra-articular knee injections improve clinical outcomes and lower health care costs. |