الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
This study was conducted to evaluate clinically and radiographically the effect of adding platelet rich plasma to Cerabone on guided bone regeneration around dental implants. The study included fourteen patients selected from the Outpatient Clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University. They were divided equally into two groups, group “1” is the control group while group “2” is the study group in which Cerabone was mixed with platelet rich plasma.
After surgical insertion of the implant fixture, either Cerabone only or Cerabone and platelet rich plasma mixture augmented the exposed implant surface. The augmentation material was covered with collagen membrane.
After Six months, the second stage surgery was performed and the final prosthesis was delivered.
Patient were evaluated clinically and radiographically for six months postoperative to asses pain, edema, wound healing, implant stability, gained bone width and bone density.
Cone beam computed tomography was obtained preoperative, immediately postoperative and after six months postoperative for assessment of labial bone width and density using Ondemand3D software.
Clinical results showed no significant difference regarding postoperative pain, edema and wound healing. Only three patients experienced wound dehiscence and edematous discharge that was resolved within two weeks postoperatively.No serious complications were noticed regarding wound infection and implant failure.Ten patients experienced mild pain (VAS=1-4) and four patients experienced moderate pain (VAS=5-7). The mean of VAS at group “1” was 4.14 and at group “2” was 3.14.Four patients of the control group and two patients of the study group presented a slight indentation that rebound within 15 seconds and the remaining patients showed a barely detectable edema.
The mean of implant stability quotient (ISQ) increased significantly during the six months healing period in both groups. However, the percentage of change in ISQ atgroup “2”was found to be higher than group “1” but statistically there was no significant difference.
Radiographic results showed that labial bone width was significantly superior at group “2” after six months postoperative. Bone density increased significantly during the healing period in both groups. The percentage of change in bone density at group “2” was higher than group “1” after six months postoperative. However, statistically there was no significant difference.