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العنوان
Design and Building of Some New Antitumor Nitrogen Heterocycles and Their Applications /
المؤلف
Farouk, Nesma Adel.
هيئة الاعداد
باحث / Nesma Adel Farouk
مشرف / Mohamed Samy EL-Gharib
مشرف / El-Sherbiny Hamdy El-Sayed
مشرف / Ahmed Ragab El-Sayed Mahdy
مناقش / Sahar Said Ahmed El- sakka
مناقش / Ashraf Abd Elaziz Elbendary
تاريخ النشر
2021.
عدد الصفحات
217 p. ;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Multidisciplinary تعددية التخصصات
تاريخ الإجازة
12/6/2021
مكان الإجازة
جامعة بورسعيد - كلية العلوم ببورسعيد - Chemistry Department
الفهرس
Only 14 pages are availabe for public view

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from 217

Abstract

This work aimed to synthesis series of organic compounds of imidazolidine moiety and study the applications of these compounds either biological applications or coordination application . So, we started the work of these series by using dihydroacetophenone thiosemicarbazone derivatives to get imidazolidine derivatives and all the structures were emphasized by use of different spectroscopic techniques, IR and 1H, 13C-NMR, along with elemental analysis. And all these compound were tested against cancers cell lines to get important results about their biological activities.Coordination application was studied by synthesis aminothiohydantoin Schiff base complexes. The two series of complexes have been succefully
synthesized. The coordination modes, stoichiometry, geometery, thermal stability, and morphology of complexes were deduced based upon the outputs of different physicochemical, spectroscopic, and microscopic techniques. Also biological activities of these complexes have been studied.