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العنوان
Assessment of choroidal changes in primary open angel glaucome using optical coherence tomography /
المؤلف
Elesawy, Sarah Ahmed Mohamed.
هيئة الاعداد
باحث / سارة أحمد محمد العيسوي
مشرف / ثروت حسنين مقبل
مشرف / إيهاب محمد نافع
مشرف / طارق أحمد عبدالوهاب محسن
الموضوع
Glaucoma.
تاريخ النشر
2021.
عدد الصفحات
107 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنصورة - كلية الطب - طب وجراحة العيون
الفهرس
Only 14 pages are availabe for public view

from 104

from 104

Abstract

Introduction Glaucoma is a progressive optic neuropathy related to retinal ganglion cell death in the optic nerve head with loss of visual field. As elevated intraocular pressure is a main risk factor for progression of glaucoma its control is a mainstay of glaucoma treatment ,despite adequate IOP control, glaucoma progression sometimes occurs In line with this, many studies have focused on ocular ischemia and the role of ocular blood supply in glaucomatous optic nerve damage The choroid is the abundant vascular layer, the blood flow of which is the highest per unit weight in the human body. The choroid provides more than 70% of the eye’s circulatory blood. In this way, it supplies nutrients to the outer retina and Optic nerve head, especially the pre laminar region, which is closely related to retinal ganglion cell death in glaucoma. Optical coherence tomography angiography (OCTA) is a new non-invasive imaging technique that employs motion contrast imaging to high-resolution volumetric blood flow information generating angiographic images in a matter of seconds. Optical coherence tomography emerged as the most useful method for measurement of choroidal thickness& measuring local circulation using high-speed OCT to perform quantitative angiography in vivo. The study concluded that there were Significant decrease in macular and peripapillary choroidal thickness in POAG patients when compared to control group with SS-OCT. Massive decrease in choroidal vessel density was detected at the ONH, and macular regions in glaucoma when Compared to healthy eyes using OCTA In this study , It was noted that glaucoma patients had significantly decreased choroidal thickness measurments than normal controls with MCT of (252.48 ± 8.62µm) in patient group while was (309.53 ± 18.90µm) in control group (P ˂ 0.001) and a mean PPCT of (214.33 ± 10.55µm) in patient group and (276.00 ± 9.95µm) in control group (P ˂ 0.001) also there is decreased VD measurments when compared to normal controls . MCVI of (50.15 ± 1.767) in patient group and (61.97 ± 2.547) in control group (P ˂ 0.001).,and PCVI of (48.02 ± 1.761) in patient group and (58.05 ± 1.168) in control group (P ˂ 0.001).