الفهرس | Only 14 pages are availabe for public view |
Abstract We aim to assess serum copper and zinc in beta thalassemia patients and there effect on patients growth and development. In acase control study comprising 100 children with beta thalassemia and 100 healthy controls.the median zinc level was significantly low in case group while median copper level was significantly higher in case group. The median serum copper and zinc levels in patients group were different according to some clinical and laboratory variables. Further patients with hypozincemia had noticeable lower ferritin level and significantly lower bone mineral density z score .also most of our patients were on deferasirox as iron chelator most of the patients receiving desferroxamine had noraml copper level. While most of patients with hypozincemia were receiving deferasirox and number of hypozincemic patients on exjade was significantly higher. Essential trace elements level changes and deficiency might occur in thalassemia major patients.obviously hypozincemia and hypercupremia were prevalent among our patients. |