الفهرس | Only 14 pages are availabe for public view |
Abstract Seaweeds are one of the most important organisms used in the extraction of biopolymers, and it is available on the Egyptian shores, as this study relates to the use of alginate extracted from the algae Cystoseira and Turbinaria and its characterization to find out its effect on phycocyanin and ketoprofen. And a study of the ability of alginates to produce silver nanoparticles using a non-toxic and environmentally friendly biological method. The ability of silver nanoparticles produced biologically by alginate to inhibit the growth of cancerous tumors as well as their ability to inhibit the growth of bacteria on surgical sutures has been studied. The main research activities and the results of the current study can be summarized as follows: Alginate was extracted and described to test its ability in biotechnological studies. The chemical characterization of alginate, which includes carbohydrates, proteins and sulfates, in addition to a UV analysis that shows the presence of the phenolic components and flavonoids. FT-IR analysis revealed the presence of O-H, COO-, C-H and S = O, indicating the presence of alcohols, proteins, carboxylic acids, and sulfates, as well as the hormone-like activity characteristic of all marine algae used. The thermal analysis revealed that the alginate is thermally stable at high temperature. Alginates were tested on the possibility of loading with C-phycocyanin, and the results showed high efficiency. The results showed high efficiency in loading microspheres with ketoprofen and that it could be used in industrial application, as they indicated the efficiency of alginate extracted from Egyptian brown algae in transporting drugs and that it is a safe carrier material that does not interact with it. Alginate solution was used in the biosynthesis of silver nanoparticles, which showed effective anti-bacterial results and had inhibitory activity for cancer cells. Its toxicity was estimated by testing microalgae. |