الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 184 |  |  |
| | | from | 184 | | |
Abstract
This in-vivo study was performed to evaluate the efficacy of resin
infiltration (ICON®) and fissure sealant (FissealTM) versus fluoride varnish
(Duraphat) in arresting or reversing initial occlusal carious lesions in
permanent teeth after one-year clinical follow-up.
Ten patients of both sexes with an age ranging between (15-25) years
were selected to participate in the present study. Each patient was examined
with DIAGNOcam and ICDAS visual criteria to select teeth having ICDAS
Code 1 and Code 2 to be sure that the caries is limited to enamel of the
occlusal surface.
Forty teeth were used in the study that were distributed as four teeth in
each patient and were divided into four groups according to the material used
for the treatment. The carious lesions of group I were infiltrated with ICON®
resin infiltrant, those of group II were sealed with a resin-based fissure
sealant (FissealTM) and those of group III were painted with Duraphat
fluoride varnish while those of group IV were left without treatment (control
groups).
All groups were subjected to a clinical follow up schedule representing
three follow up periods (baseline, after 6 and 12 months) during which, the
efficacy of each material in arresting caries progression was assessed
radiographically through the subtraction of pixel grey value measurements
using bitewing digital radiographs. 1st subtraction, showing the effect of the
materials in the first evaluation period (subtracting the baseline values from
those after 6 months), 2nd subtraction showing the effect of the materials in
the 2nd evaluation period (subtracting values of 6 from those after 12
months). The 3rd subtraction (subtracting the baseline values from those afterCH.VII Summary & Conclusions
90
12 months) revealed the final effect of the tested materials. The marginal
integrity of the tested materials was examined under the scanning electron
microscope using epoxy resin replicas of randomly selected patients.
The results of current study revealed a slight progression in group I
(treated with Icon®) followed by group II (treated with FissealTM) then group
III (treated with Duraphat) while group VI (left without treatment) showed a
sever progression at the different evaluation periods.
No significant difference between group I and group II was recorded
denoting nearly similar effect of ICON® resin infiltrant and FissealTM fissure
sealer on the initial lesions caries progression. This was confirmed by SEM
images showing complete marginal adaptation of the materials in both
groups. However, group III showed complete loss of the material represented
by a pseudo gap formation. Statistical analysis recorded that both groups
were significantly different from group III revealing weak effect of fluoride
varnish in retarding the caries progression. None of the treatment modalities
reversed or arrested initial occlusal carious lesion progression thus the
current hypothesis was rejected.