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العنوان
Studies on bioglass doped with cerium/
المؤلف
Abd-Alraziq,Alshimaa Ali .
هيئة الاعداد
باحث / الشيماء علي عبدالرازق
مشرف / معوض محمد الخولى
مشرف / لبني محمد شرف الدين
مشرف / بثينة محمد عبد الهادي
الموضوع
Physics. Silicate Based Bioactive Glasses. Bioactive Glasses . Polymers. Scaffolds for Tissue Engineering. Scaffold Fabrication.
تاريخ النشر
2020.
عدد الصفحات
136 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الفيزياء والفلك (المتنوعة)
تاريخ الإجازة
19/2/2020
مكان الإجازة
جامعة المنوفية - كلية العلوم - الفيزياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

As the average age of people increases, there is a growing demand
for materials that enhance the repair and regeneration of the bones.
Biomaterial is any substance or blend of substances that can be utilized in
general or as a piece of a framework in the human body to improve
physiological function and quality of life. Bioactive silicate glasses
present great advantages as biomaterials, due to their high bioactivity and
their ability to make bonds with both soft and hard tissues. Therefore,
silicate bioactive glass has been subjected to extensive research.
Properties of bioactive glasses can be modified by addition a small
amount of various elements which make the material more compatible for
different clinical applications. The main objectives of our study are
fabrication a novel silicate bioactive glass and investigation the influence
of cerium doping on the prepared bioactive glass then apply the doped
bioactive glass in the polymer scaffolds.
The thesis consists of three chapters as follow:
Chapter one: This chapter contains introduction about bioactive
glasses and literature review.
Chapter two: This chapter contains two parts, the first part
presents the used materials and the research methodology for: synthesis
of nanoparticle bioactive glass powder composed of 52 wt. % SiO2, 41
wt. % CaO, 7 wt. % P2O5 via sol –gel method, synthesis of cerium doped
nanoparticles bioactive powders which composed of [52 SiO2, (41-x)
CaO, 7 P2O5, xCe2O3] with x= 2.0, 4.0, 6.0 and 8.0 in (wt. %),
preparation of simulated body fluid and fabrication of porous a 3D
composite scaffold from blending of (HEC/PVP) polymer and bioactive
glass doped with 8% cerium oxide. The second part of this chapter is devoted for instruments which were used for the characterization of
prepared glass samples and scaffolds.
Chapter three: This chapter consists of three separate parts; the
first is concerned with the results of silicate bioactive glass nanoparticles.
Structure and bioactivity of the prepared powder have been investigated
using various techniques. Also, the specific surface area and mean pore
size of the prepared glass powders have been examined and the second
part presents the investigation of doping effect on the prepared
nanostructure bioactive glass with different concentrations of cerium
oxide. The third part deals with the characterization`s results of the
prepared composite scaffolds from blending of (HEC/PVP) polymer and
8% cerium oxide doped bioactive glass nanoparticles. At the end of this
chapter, there is a conclusion of the three chapters.