الفهرس 
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Abstract
Lung cancer is the leading cause of cancer related deaths worldwide. Adenocarcinoma (AC) and squamous cell carcinoma (SCC) are the two most common histological sub-types of lung cancer. We have to differentiate between these two sub-types, because this determines the eligibility of the patient for specific molecular testing and therapeutic strategies.
PET-CT is used in the diagnosis, staging and follow up of lung cancer patients. SUVmax is the most widely used parameter to measure the metabolic activity of the lesions in PET-CT scans. Tumor-to-liver ratio (TLR) is an arising concept aiming to normalize the SUVmax of the lesion to the SUV of the liver. We tried to use the SUVmax and TLR as a reference to differentiate between AC and SCC of the lung.
In our study, we found that we can discriminate between AC and SCC of the lung by the size of the lesion (measured as maximal tumor diameter), the SUVmax of the lesion, and the TLR. SCC attains more values compared to that of AC of the lung.
All three parameters show the same sensitivity, however the TLR shows the highest specificity followed by tumor size then SUVmax of the tumor.
In summary, PET-CT can be used to differentiate between AC and SCC of the lung using several variables.