الفهرس 
Introduction and Aim of workOnly 14 pages are availabe for public view
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Abstract
Medicine is an art that is based largely on balancing probabilities, whether these probabilities relate to diagnosis, prognosis, or response to treatment, clinical practice is generally easier when we have information that allows us to estimate probabilities for individual patients. Information on prognosis is particularly useful , and methods of prediction of outcome have been developed in virtually all branches of medicine . Stroke is not exception, and there is a large literature on prediction of stroke occurrence in various settings (Kernan et al., 2000) .
Cerebrovascular stroke is one of the most frequent causes of death and disability worldwide, It has significant clinical and socioeconomic impact. Outcome after ischemic stroke depends on a complex interaction of multiple factors that contribute to the balance towards either a favorable or unfavorable outcome. The expanding use of biomarkers in the field of stroke has made a substantial impact in our understanding of the pathophysiology of stroke and the approach to treatment. ( Matthew and Karen , 2009). Various markers have been evaluated for their association with prospective risk for stroke, for diagnostic purposes and for their value in predicting long-term outcome. Markers of risk factors and prevention strategies have been extensively reviewed in treatment guidelines. The American Stroke Association (ASA) guidelines for stroke prevention contain a thorough review of the markers of prospective stroke risk for primary and secondary prevention .The use of biomarkers in diagnosing stroke and assessing prognosis is an emerging and rapidly evolving field . (Goldstein et al., 2006).