الفهرس 
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Abstract
Equine lungs are commonly affected by many diseases of variable causes which are either due to infectious or non-infectious causes. A total of hundred donkey lungs were collected (2016-2017) from Giza zoo animal slaughterhouse. Postmortem, histopathological, histochemical and immunohistochemical examination of any pulmonary affections were performed. The equine herpesvirus 1 (EHV1) and myofibroblast were immunohistochemically stained in pneumonic and pulmonary fibrosis cases respectively. The incidence of emphysema was 72% whereas edema 25%, hemorrhage 27%, Inflammatory Airway Disease (IAD) 78%, pneumonia 66%, parasitic affection 9% and pulmonary fibrosis (PF) 19%. EHV1 was positive in observed interstitial pneumonia and in association with cases of pulmonary fibrosis. α-SMA was positively expressed in myofibroblasts present in focal and diffuse PF emphasizing on the role of myofibroblasts in the pathogenesis of PF. This study showed a high incidence of the pulmonary affections in donkeys. EHV1 was diagnosed in interstitial pneumonia and in pulmonary fibrosis which suggests that EHV1 may have a role in PF. In horse cases, neonatal death with EHV1 infection was confirmed in foal aged 3days. Other lesions observed in horses included eosinophilic pneumonia, Interstitial pneumonia, bronchinterstitial pneumonia, inflammatory airway disease, interstitial fibrosis, and exudative bronchopneumonia.