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العنوان
Hematological indices in ischemic heart disease with impaired left ventricle systolic function /
المؤلف
Mohammed, Mahmoud Bahaa El-Din.
هيئة الاعداد
باحث / محمود بهاءالدين محمد محمد بركات
مشرف / نادر الشحات عوض
مشرف / محمود عبدالبديع سالم
مناقش / شريف عبد السلام صقر
مناقش / حمزه محمد سعد قابيل
الموضوع
Coronary heart disease - Treatment. Myocardial infarction. Ventricular fibrillation. Myocardial Ischemia. Coronary disease.
تاريخ النشر
2019.
عدد الصفحات
online resource (122 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
01/01/2019
مكان الإجازة
جامعة المنصورة - مركز تقنية الاتصالات والمعلومات - Cardio vascular Department
الفهرس
Only 14 pages are availabe for public view

from 122

from 122

Abstract

Coronary heart disease (CHD), most commonly caused by atherosclerosis, one of most common causes of death worldwide. Atherosclerosis is a systemic, lipid-driven immune inflammatory disease. Inflammation is one of the factors leading to coronary artery disease (CAD), which can be not only local but also systemic. It was proved that myocardial infarction is linked to an increased myeloid activity. Interestingly, it has been shown that in the case of mice with an induced myocardial infarction, the sympathetic nervous system becomes activated, This in turn induces the release of hematopoietic stem cells from bone marrow niches, which consequently causes the further systemic stimulation of atherosclerotic plaques. In recent years, strong interest has arisen in the main hematological indices, given that they may provide independent information on pathophysiology, risk stratification, and optimal management. The main advantage of hematological indices that they are relatively inexpensive and thus widely and easily available in daily clinical practice. They have also proven their diagnostic and prognostic value in many cardiovascular diseases including CAD. Cardiomyopathies (CMP) are a group of disorders characterized by dilatation and impaired contraction of left ventricle (LV) and, thromboembolic event is a serious complication in these patients. At least 11% of patients with dilated CMP have one or more embolic event during the course of this illness, and mural thrombus is more frequently observed in the LV than in the left atrium.