الفهرس 
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Abstract
Background: Coronary artery disease (CAD) is one of the most common causes of mortality worldwide. Recent evidence has demonstrated an important role of inflammation in atherosclerosis. Neutrophil- to- Lymphocyte ratio (NLR) is an emerging biomarker of inflammation.
Objective: The aim of our study is to investigate the relation between NLR and atherosclerotic CAD in type 2 diabetes mellitus (T2DM) patients using multisclice computed tomography (MSCT).
Patients and methods: Our study was conducted upon 60 T2DM patients presented to Ain Shams and Misr University hospitals and were referred to do MSCT for assessment of CAD. All segments of the coronary arteries were examined and were divided into 16 segments according to the modified American heart association classification. Patients were divided into groups according to presence of CAD as normal and ischemic heart disease and those with ischemic heart disease were subdivided according to the degree of luminal stenosis as non-obstructive (<50% luminal stenosis) and obstructive (≥50% luminal stenosis) CAD. Other coronary CT angiographic scores were also used as atheroma burden obstructive score (ABOS), segment involvement score (SIS) and segment stenosis score (SSS).
Results: It was found in our study that no statistical significance is present between NLR and presence of CAD. However, male gender, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and red cell width (RDW) were found to be significantly associated with CAD. Also, upon studying the correlation between NLR and severity of CAD there was no statistical significance and only the MCV was associated with severity of CAD.
Conclusion: The present study concluded that there is no significant correlation between the NLR and presence and/or severity of ischemic heart disease in T2DM patients. Other CBC indices were found to be significantly related to ischemic heart disease as MCV, MCH and RDW.