الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 216 |  |  |
| | | from | 216 | | |
Abstract
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. The prevalence of PCOS is about 6% to 8% among reproductive-age women. Long-term PCOS increases the risk of endometrial hyperplasia, cancer, type 2 diabetes, cardiovascular diseases and cardiac arrest during sleep. In addition, there are ovulatory dysfunction, infertility, increased anxiety, depression and several other complications.
Imbalance between pro-oxidant molecules and antioxidant defensive system may result in PCOS. Broccoli (Brassica oleracea) has wide range of pharmacological activities including phytoestrogenic, antioxidant, anti-inflammatory, antimicrobial, antidiabetic and hypolipidemic effects in addition to its anti-cancer properties.
The present study was performed to induce a rat model of PCOS by estradiol valerate (EV) and to investigate possible protective or therapeutic role of broccoli extract in adult female albino rat.