الفهرس 
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Abstract
Coronary artery disease (CAD) is the leading cause of cardiovascular mortality worldwide, with more than 4.5 million deaths occurring in the developing world. Although CAD is considered a macro vascular disease, microangiopathy has been observed to play a role in its pathogenesis. Retina is the only place in the body where micro vascular damage can be observed directly.
Atherosclerosis is a systemic disease that affects many arterial beds in the body, such as the retinal vasculature. Some studies show the associations of retinal arteriolar abnormalities with clinical and subclinical manifestations of atherosclerosis and with risk factors for vascular disease. Structural changes in the retinal vasculature are considered as main indicators of systemic hypertensive damage and life prognosis
The aim of our study is to investigate the frequency of retinal arteriolar findings diagnosed by ophthalmoscopy in hypertensive patients presented with angina and the correlation between retinal changes and severity of CAD diagnosed by coronary angiography.
The current study was conducted at Minia University Hospital during period from June 2015 and July 2017. This study include 80 hypertensive patients presented with angina .
All patients were subjected to the following:
1. History taking.
2. Clinical examination.
3. Blood pressure measurement.
4. Resting twelve lead ECG.
5. Stress ECG.
6. Transthoracic echocardiography.
7. Coronary angiography.
8. Fundus examination.
The result show that retinal vessel atherosclerosis correlates strongly with atherosclerotic changes in coronary arteries in hypertensive patients and the changes were much more in patients with uncontrolled hypertension.