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العنوان
Mass Spectra Investigation And Biological Evaluation Of Some Prepared Nitrogen Heterocycles /
المؤلف
Hegazy, Sara Adel Abu El-ata.
هيئة الاعداد
مناقش / Maher Abd el-aziz Mahmoud El-hashash
مناقش / Ahmed Ali Hamed Fadda
مناقش / Ibrahim El-Sayed Mohey El-Deen
مشرف / Ibrahim Mohey El-Deen
مشرف / Elsherbiny Hamdy Elsayed
مشرف / Amal Mahmoud Youssef Moustafa
الموضوع
chemistry.
تاريخ النشر
2018.
عدد الصفحات
122 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
5/1/2019
مكان الإجازة
جامعة بورسعيد - كلية الهندسة ببورسعيد - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

This thesis divided into two parts, as follows:
part One:
Synthesis Of New 2-N-Substitutedamino-5-aryl-1,3-thiazoles As Antitumor Agents
This section contains the manufacture of new thiazole derivatives, chemical structure of the new 1,3-thiazole derivatives has been demonstrated by chemical and spectral methods (IR, NMR and mass spectrometry).
The biological activity of thiazole and carbazone derivatives, which were prepared as anti-cancer drugs against two different cancer cell lines (breast cancer cell line, liver cancer cell line).
Part two:
Synthesis and Biological Evaluation of Some Novel 2-Thiohydantoin Derivatives As Apoptosis Inducer
This part contains the design, synthesis, and biological evaluation of new derivatives of thiohydantoin.