الفهرس | Only 14 pages are availabe for public view |
Abstract Our study was done to explore relationship between H. pylori infection and irritable bowel syndrome as regard type, its severity and complications, This study will be performed on 80 patient attended GIT out patient clinic of sohag university hospital from 6/2017to 3/2018 will be classified into 1-controle group (20patients)who do not fulfill criteria for diagnosis of irritable bowel syndrome 2-Affected group(60patients) who fulfill criteria for diagnosis of irritable bowel syndrome Those groups will be classified according to severity Also the affected groups will be classified according to subtypes All patents underlying the following: (1) history will be taken including: (2) Examination: (2)Full clinical examination (3) Laboratory investigations • Fasting blood glucose level,HBA1C • renal function .liver function, complete blood counting • Abdominal ultrasonography • H.pylori stool antigen test titr (SATA) Our study revealed that Stool antigen test titre(SAT) was done for all studied cases and about 43 patients (53.75%) were SAT positive and about 37 patients (46.25%) were SAT negative Distribution of studied population according to H.Pylori SAT 46% SAT negative ,53.7% sat positive Comparison was done among all types of IBS as regard H.Pylori SAT revealed constipation predominant cases have the highest number(33%) of H.Pylori SAT positive cases while lowest number of cases(4%) were unclassified,Comparison was done among all grades of IBS as regard H. Pylori SAT revealed grade 3 cases the highest number of H. Pylori SAT positive cases, lowest number of cases were grade1 Conclusion In this study revealed positive relationship between H . Pylori infection and irritable bowel syndrome as regard types of irritable bowel syndrome, the incidence of H. Pylori infection was more with constipation predominant patients and as regard severity of irritable bowel syndrome , H . Pylori infection more common in grade 3 . Recommendation : This study affected by limited number of cases, specificity and sensitivity of SAT ELISA APPARATUS, more researches are need to be done to explore this relation , and to explore the effect of H . Pylori eradication therapy on improvement of symptoms of irritable bowel syndrome which may help in adding TTT of H . Pylori infection as a line of management of IBS. |