الفهرس 
Diabetic Kidney DiseaseOnly 14 pages are availabe for public view
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Abstract
Background and Aim: Diabetes Mellitus (DM) is a complex chronic disorder in carbohydrates metabolism manifested by fasting and/or postprandial hyperglycemia. DM causes serious complications on long term which include cardiovascular diseases, damage to blood vessels and nerves causing angiopathy and neuropathy, impairment in circulation leading to diabetic foot amputation and defect in many metabolic processes causing damage to the kidneys leading to Diabetic Kidney Disease (DKD). Beta Trace protein (BTP), known as lipocalin prostaglandin D2 synthase (L-PGDS), is a low molecular weight glycoprotein and considered another marker of glomerular filtration rate.
The study aimed at following up patients from Damietta governorate with type 2 DM for 3 months for assessment of BTP level and determine its possible role in early detection of Diabetic Nephropathy beside 10 healthy individuals as control group. All participants were subjected to measurement of BTP using enzyme-linked immunosorbent assay in addition to urinary albumin creatinine ratio at selection and after 3 months of follow up.
Patient and Methods: This is a prospective study. This study was carried-out between January 2015 and July 2015 on 40 patients from Damietta Governorate with newly diagnosed type II Diabetes Mellitus and 10 healthy control subjects with no history of Diabetes Mellitus or Kidney disease. Patients will be followed for 3 months.
Result: The results of the study showed that BTP have higher frequency in diabetic patients than control individuals.
Conclusion: Beta Trace Protein (BTP) is a promising biomarker for early detection of diabetic kidney disease in Type 2 Diabetes Miletus before the development of Microalbuminuria and elevation of kidney functions.